Power to Quit

Smoking Characteristics and Comorbidities in the Power To Quit Randomized Clinical Trial for Homeless Smokerspower to quit

Principal Investigator

Kola S. Okuyemi, MD, MPH  


Kate Goldade, PhD; Guy-Lucien Whembolua, PhD; Janet L. Thomas, PhD; Sara Eischen, BA; Hongfei Guo, PhD; John E. Connett, PhDJon Grant, MD, JD; Jasjit S. Ahluwalia, MD, MPH; Ken Resnicow, PhD; Greg Owen, PhD; Lillian Gelberg, MD, MSPH; Don Des Jarlais, PhD 


National Heart Lung and Blood Institute (R01HL081522)


Smoking prevalence in homeless populations is strikingly high, 70% or greater, however, little is known about effective smoking cessation interventions for this population. By conducting a community-based clinical trial, Power to Quit (PTQ), researchers assessed the effects of motivational interviewing (MI) and nicotine patch (nicotine replacement therapy (NRT)) on smoking cessation among homeless smokers. Using a sample size of 430 homeless adult smokers, this study enabled researchers to examine the influence that nicotine dependence, substance abuse, and mental health play in smoking cessation outcomes. 


  • Goldade K, Whembolua GL, Thomas J, Eischen S, Gelberg L, Des Jarlais D, Grant J, Connett JE, Guo H, Ahluwalia JS, KS Okuyemi. Designing a Smoking Cessation Trial for the Unique Needs of Homeless Persons: A Community Based Randomized Clinical Trial. Clinical Trials: Journal of the Society for Clinical Trials, 2011; 8:744-54. Contribution: Defined intellectual content, conducted literature research manuscript preparation, editing, and review. Impact Factor: 2.632
  • Goldade K, Whembolua, G, Des Jarlais, D, Owen, G, Okuyemi, KS. Homeless Former Smokers’ Interest in Helping Homeless Current Smokers Quit. American Journal of Health Promotion. 2012 Nov-Dec;27(2):90-3. Contribution: Data acquisition, manuscript preparation, editing, and review. Impact Factor: 2.37